Protection by Ziziphora clinopoides of acetic acid-induced toxic bowel inflammation through reduction of cellular lipid peroxidation and myeloperoxidase activity.

@article{Ghafari2006ProtectionBZ,
  title={Protection by Ziziphora clinopoides of acetic acid-induced toxic bowel inflammation through reduction of cellular lipid peroxidation and myeloperoxidase activity.},
  author={Homanaz Ghafari and Narges Yasa and Azadeh Mohammadirad and Gholamreza Dehghan and Mohammad Jafar Zamani and Shokoufeh Nikfar and Reza Khorasani and Bagher Minaie and Mohammad Abdollahi},
  journal={Human & experimental toxicology},
  year={2006},
  volume={25 6},
  pages={325-32}
}
Inflammatory bowel disease (IBD) is a chronic condition of the intestine with unknown etiology involving multiple immune, genetic and environmental factors. We were interested in examining the effect of a total extract from Ziziphora clinopoides, an Iranian folk herbal medicine, in the prevention and control of experimental mouse IBD. Z. clinopoides was administered (75, 150, 300 mg/kg) through drinking water to mice, which dispensed a toxic dose of acetic acid intrarectally. Prednisolone was… CONTINUE READING