Protection against severe rotavirus diarrhoea by rhesus rotavirus vaccine in Venezuelan infants.

@article{Flores1987ProtectionAS,
  title={Protection against severe rotavirus diarrhoea by rhesus rotavirus vaccine in Venezuelan infants.},
  author={Jorge Flores and Irene P{\'e}rez-Schael and Marco Antonio de la Serna Gonz{\'a}lez and Dania Garc{\'i}a and Miguel Angel Abian Perez and Nabil Daoud and Walter Cunto and Robert M. Chanock and Albert Z. Kapikian},
  journal={Lancet},
  year={1987},
  volume={1 8538},
  pages={882-4}
}
The efficacy of the rhesus rotavirus vaccine candidate MMU-18006 was evaluated in a longitudinal double-blind field trial in Caracas, Venezuela. 247 infants aged 1-10 months were studied and followed for up to 1 year (201 completed the 1-year surveillance): 123 received a dose of 10(4) plaque-forming units of the vaccine orally and 124 received placebo. 21 episodes of rotavirus diarrhoea were detected, 16 in the controls and 5 in the vaccines: vaccine efficacy against any rotavirus diarrhoea… CONTINUE READING

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