Protection against radiation-induced oxidative damage by an ethanolic extract of Nigella sativa L.

@article{Rastogi2010ProtectionAR,
  title={Protection against radiation-induced oxidative damage by an ethanolic extract of Nigella sativa L.},
  author={Lori Rastogi and Shaikh Feroz and B N Pandey and A. G. Jagtap and Kaushala Prasad Mishra},
  journal={International journal of radiation biology},
  year={2010},
  volume={86 9},
  pages={719-31}
}
PURPOSE An ethanolic extract of Nigella sativa L. (EE-NS) was investigated for its antioxidant properties and radioprotective effects against gamma-radiation-induced oxidative damage. MATERIALS AND METHODS The radical scavenging activity of the extract was measured by 2,2-diphenyl-1-picrylhydrazyl (DPPH), deoxyribose degradation and plasmid relaxation assays in a cell-free system. DNA damage studies were performed using a single cell gel electrophoresis (SCGE) assay and micronuclei (MN… CONTINUE READING

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