Protection against pneumococcal sepsis in splenectomized rats by implantation of splenic tissue into an omental pouch.

@article{Patel1982ProtectionAP,
  title={Protection against pneumococcal sepsis in splenectomized rats by implantation of splenic tissue into an omental pouch.},
  author={Jeetendra Kumar Patel and James Scott Williams and John Naim and J R Hinshaw},
  journal={Surgery},
  year={1982},
  volume={91 6},
  pages={638-41}
}
Clinical and laboratory studies have documented high susceptibility to pneumococcal infection in asplenic humans and animals. Surgeons have stressed the need to preserve the spleen when possible to maintain host resistance. It has been suggested that autotransplantation of splenic tissue might be a method of providing host resistance when total splenectomy is necessary. However, previous studies of rats have failed to demonstrate any protective effect of autotransplanted spleen. This study… CONTINUE READING

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