Protection against hepatic ischemia-reperfusion injury in rats by oral pretreatment with quercetin.

@article{Su2003ProtectionAH,
  title={Protection against hepatic ischemia-reperfusion injury in rats by oral pretreatment with quercetin.},
  author={Jun-feng Su and Chang-jiang Guo and Jing-yu Wei and Ji-jun Yang and Yu-gang Jiang and Yun-Feng Li},
  journal={Biomedical and environmental sciences : BES},
  year={2003},
  volume={16 1},
  pages={
          1-8
        }
}
OBJECTIVE To investigate the possible protection provided by oral quercetin pretreatment against hepatic ischemia-reperfusion injury in rats. METHODS The quercetin (0.13 mmol/kg) was orally administrated in 50 min prior to hepatic ischemia-reperfusion injury. Ascorbic acid was also similarly administered. The hepatic content of quercetin was assayed by high performance liquid chromatography (HPLC). Plasma glutamic pyruvic transaminase (GPT), glutamic oxaloacetic transaminase (GOT) activities… CONTINUE READING

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