Protection against a European H1N2 swine influenza virus in pigs previously infected with H1N1 and/or H3N2 subtypes.

@article{Reeth2003ProtectionAA,
  title={Protection against a European H1N2 swine influenza virus in pigs previously infected with H1N1 and/or H3N2 subtypes.},
  author={Kristien van Reeth and Vicki L. Gregory and A. -E. Hay and Maurice B Pensaert},
  journal={Vaccine},
  year={2003},
  volume={21 13-14},
  pages={1375-81}
}
A novel swine influenza virus, H1N2, circulates in European swine populations together with H1N1 and H3N2 viruses. This study examines whether post-infection immunity to H1N1 and/or H3N2 viruses provides cross-protection against H1N2 infection. Pigs (n=51) were inoculated intranasally with either Sw/Belgium/1/98 (H1N1) or Sw/Flanders/1/98 (H3N2), or with both viruses at a 5-week interval. Control groups were left uninoculated or inoculated with Sw/Gent/7625/99 (H1N2). Four weeks later, all the… CONTINUE READING

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