Protection against P. aeruginosa with an adenovirus vector containing an OprF epitope in the capsid.

@article{Worgall2005ProtectionAP,
  title={Protection against P. aeruginosa with an adenovirus vector containing an OprF epitope in the capsid.},
  author={Stefan Worgall and Anja Krause and Michael Rivara and K Hee and Enrico V Vintayen and Neil R. Hackett and Peter W. Roelvink and Joseph T. Bruder and Thomas J. Wickham and Imre Kovesdi and Ronald G. Crystal},
  journal={The Journal of clinical investigation},
  year={2005},
  volume={115 5},
  pages={1281-9}
}
Pseudomonas aeruginosa is an important opportunistic pathogen that can cause chronic and often life-threatening infections of the respiratory tract, particularly in individuals with cystic fibrosis (CF). Because infections with P. aeruginosa remain the major cause of the high morbidity and mortality of CF, a vaccine against P. aeruginosa would be very useful for preventing this disorder. The outer membrane protein F (OprF) of P. aeruginosa is a promising vaccine candidate and various B cell… CONTINUE READING