Protection against Candida albicans gastrointestinal colonization and dissemination by saccharides in experimental animals.

@article{Ghannoum1991ProtectionAC,
  title={Protection against Candida albicans gastrointestinal colonization and dissemination by saccharides in experimental animals.},
  author={Mahmoud Afif Ghannoum and Khaled H. Abu-Elteen and Ashraf S Ibrahim and R. J. Stretton},
  journal={Microbios},
  year={1991},
  volume={67 271},
  pages={95-105}
}
Pre- or post-treatment of duodenal discs with mannose, N-acetylglucosamine or chitin soluble extracts (CSE) prevented the adherence of Candida albicans to gastrointestinal tract. CSE was the most effective in blocking the adherence of C. albicans. Treatment of infant mice with saccharides significantly reduced the systemic spread of C. albicans inoculated into the gut. The best protection was obtained when the saccharides were given 2 days prior to the infection and continued over the course of… CONTINUE READING