Protecting the next generation--eliminating perinatal HIV-1 infection.

  title={Protecting the next generation--eliminating perinatal HIV-1 infection.},
  author={Lynne Mofenson},
  journal={The New England journal of medicine},
  volume={362 24},
More than 90% of the 430,000 human immunodeficiency virus type 1 (HIV-1) infections in children each year occur in sub-Saharan Africa, where HIV-1 acquisition through breast milk accounts for more than 40% of infections. However, in Africa, breast-feeding is a cornerstone of child survival. Two randomized trials reported in this issue of the Journal1,2 show that antiretroviral regimens in breast-feeding infants or lactating mothers significantly decrease postnatal acquisition of HIV-1. It… CONTINUE READING


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