Protecting the mitochondrial powerhouse.

@article{ScheibyeKnudsen2015ProtectingTM,
  title={Protecting the mitochondrial powerhouse.},
  author={Morten Scheibye-Knudsen and Evandro Fei Fang and Deborah L. Croteau and David M Wilson and Vilhelm A. Bohr},
  journal={Trends in cell biology},
  year={2015},
  volume={25 3},
  pages={158-70}
}
Mitochondria are the oxygen-consuming power plants of cells. They provide a critical milieu for the synthesis of many essential molecules and allow for highly efficient energy production through oxidative phosphorylation. The use of oxygen is, however, a double-edged sword that on the one hand supplies ATP for cellular survival, and on the other leads to the formation of damaging reactive oxygen species (ROS). Different quality control pathways maintain mitochondria function including… CONTINUE READING
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