Proteasome subunit Rpn13 is a novel ubiquitin receptor.


Proteasomal receptors that recognize ubiquitin chains attached to substrates are key mediators of selective protein degradation in eukaryotes. Here we report the identification of a new ubiquitin receptor, Rpn13/ARM1, a known component of the proteasome. Rpn13 binds ubiquitin through a conserved amino-terminal region termed the pleckstrin-like receptor for… (More)
DOI: 10.1038/nature06926


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@article{Husnjak2008ProteasomeSR, title={Proteasome subunit Rpn13 is a novel ubiquitin receptor.}, author={Koraljka Husnjak and Suzanne Elsasser and Naixia Zhang and Xiang Chen and Leah Randles and Yuan Shi and Kay Hofmann and Kylie J. Walters and Daniel Finley and Ivan Dikic}, journal={Nature}, year={2008}, volume={453 7194}, pages={481-8} }