Proteasome regulation of the chromodomain protein MRG-1 controls the balance between proliferative fate and differentiation in the C. elegans germ line.

Abstract

The level of stem cell proliferation must be tightly controlled for proper development and tissue homeostasis. Multiple levels of gene regulation are often employed to regulate stem cell proliferation to ensure that the amount of proliferation is aligned with the needs of the tissue. Here we focus on proteasome-mediated protein degradation as a means of… (More)
DOI: 10.1242/dev.115147

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Cite this paper

@article{Gupta2015ProteasomeRO, title={Proteasome regulation of the chromodomain protein MRG-1 controls the balance between proliferative fate and differentiation in the C. elegans germ line.}, author={Pratyush Gupta and Lindsay Leahul and Xin Wang and Chris Wang and Brendan Bakos and Katie Jasper and Dave Hansen}, journal={Development}, year={2015}, volume={142 2}, pages={291-302} }