Proteasomal components required for cell growth and stress responses in the haloarchaeon Haloferax volcanii.

@article{Zhou2008ProteasomalCR,
  title={Proteasomal components required for cell growth and stress responses in the haloarchaeon Haloferax volcanii.},
  author={Guangyin Zhou and David F Kowalczyk and Matthew A. Humbard and Sunil Rohatgi and Julie A Maupin-Furlow},
  journal={Journal of bacteriology},
  year={2008},
  volume={190 24},
  pages={8096-105}
}
Little is known regarding the biological roles of archaeal proteases. The haloarchaeon Haloferax volcanii is an ideal model for understanding these enzymes, as it is one of few archaea with an established genetic system. In this report, a series of H. volcanii mutant strains with markerless and/or conditional knockouts in each known proteasome gene was systematically generated and characterized. This included single and double knockouts of genes encoding the 20S core alpha1 (psmA), beta (psmB… CONTINUE READING

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