Proteases and Their Inhibitors in Cancer Metastasis

  title={Proteases and Their Inhibitors in Cancer Metastasis},
  author={R. Ablin and Wen Jiang and J. -M. Foidart and Ruth J. Muschel and Constance E. Brinckerhoff and Ulrike Benbow and Yves A DeClerck and B{\'e}atrice Nawrocki-Raby and Christine E Clavel and Myriam Polette},
  booktitle={Cancer Metastasis — Biology and Treatment},
Proteinases play a central role in the complex response of tissues to injury by influencing cellular behavior and matrix remodeling. Considerable information on the biology of proteinases has been derived from gene targeting and gene transfer studies. One of the best characterised proteinase systems is the plasminogen system, belonging to the large serine… CONTINUE READING