Protease inhibitors in middle ear effusions.

As the presence of granulocytes in middle ear fluid in serous otitis media implicates a potential risk of extracellular release of granulocyte proteases, the main protease inhibitors in serum, alpha 1-antitrypsin, alpha 1-antichymotrypsin and alpha 2-macroglobulin, were immunochemically quantitated in such effusions. The mean concentration of alpha 1… (More)