Protease imaging of human atheromata captures molecular information of atherosclerosis, complementing anatomic imaging.

Abstract

OBJECTIVE There is hope that molecular imaging can identify vulnerable atherosclerotic plaques. However, there is a paucity of clinical translational data to guide the future development of this field. Here, we cross-correlate cathepsin-B or matrix metalloproteinase-2/-9 molecular optical imaging data of human atheromata or emboli with conventional imaging… (More)
DOI: 10.1161/ATVBAHA.109.194613

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