Protease-antiprotease imbalance in inflammatory diseases in the lung.


We are very interested in the extensive research by Vernooy et al,1 who addressed the importance of matrix metalloproteases (MMPs) in the pathogenesis and/or the development of COPD. It is likely to be important to evaluate the activity of the proteases rather than the expression of MMPs. Protease/antiprotease imbalance has also been postulated to be… (More)

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