Protean manifestations of lipoid proteinosis in a 16-year-old boy.

  title={Protean manifestations of lipoid proteinosis in a 16-year-old boy.},
  author={Tetsuo Nagasaka and Masaru Tanaka and Daisuke Ito and Keiko Tanaka and Hiroshi Shimizu},
  journal={Clinical and experimental dermatology},
  volume={25 1},
We report a 16-year-old Japanese male with lipoid proteinosis showing various skin manifestations. The patient was born to nonconsanguineous parents and none of his relatives was similarly affected. The patient suffered from a hoarse voice and refractory temporal epilepsy from early childhood. Computed tomography scanning of the brain showed bilateral calcification in the temporal lobes, a characteristic feature of lipoid proteinosis. On physical examination, various skin manifestations… CONTINUE READING