Protamine-carboxymethyl cellulose magnetic nanocapsules for enhanced delivery of anticancer drugs against drug resistant cancers.

@article{Elumalai2015ProtaminecarboxymethylCM,
  title={Protamine-carboxymethyl cellulose magnetic nanocapsules for enhanced delivery of anticancer drugs against drug resistant cancers.},
  author={Rajasegaran Elumalai and Shilpa S. Patil and Naseer Maliyakkal and Annapoorni Rangarajan and Paturu Kondaiah and Ashok M Raichur},
  journal={Nanomedicine : nanotechnology, biology, and medicine},
  year={2015},
  volume={11 4},
  pages={969-81}
}
UNLABELLED Multidrug resistance is a major therapeutic challenge faced in the conventional chemotherapy. Nanocarriers are beneficial in the transport of chemotherapeutics by their ability to bypass the P-gp efflux in cancers. Most of the P-gp inhibitors under phase II clinical trial are facing failures and hence there is a need to develop a suitable carrier to address P-gp efflux in cancer therapy. Herein, we prepared novel protamine and carboxymethyl cellulose polyelectrolyte multi-layered… CONTINUE READING
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Targeted nanomedicine for cancer therapeutics: Towards precision medicine overcoming drug resistance.

Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy • 2017

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