Prosthesis-patient mismatch in high-risk patients with severe aortic stenosis: A randomized trial of a self-expanding prosthesis.

@article{Zorn2016ProsthesispatientMI,
  title={Prosthesis-patient mismatch in high-risk patients with severe aortic stenosis: A randomized trial of a self-expanding prosthesis.},
  author={George L Trip Zorn and Stephen H. Little and Peter N Tadros and George Michael Deeb and Thomas G. Gleason and John C Heiser and Neal S. Kleiman and Jae Kon Oh and Jeffrey J. Popma and David H Adams and Jian Huang and Michael J. Reardon},
  journal={The Journal of thoracic and cardiovascular surgery},
  year={2016},
  volume={151 4},
  pages={1014-22, 1023.e1-3}
}
OBJECTIVES We compared the incidence of prosthesis-patient mismatch (PPM) between transcatheter aortic valve replacement (TAVR) using a self-expanding bioprosthesis and surgical aortic valve replacement (SAVR) in the CoreValve US High Risk Pivotal Trial. We sought to determine the influence of PPM on clinical outcomes. METHODS Patients with severe aortic stenosis and at increased risk for surgery were randomized 1:1 to TAVR or SAVR. Postoperative PPM was defined by the effective orifice area… CONTINUE READING
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