Prostate tissue composition and response to finasteride in men with symptomatic benign prostatic hyperplasia.

@article{Marks1997ProstateTC,
  title={Prostate tissue composition and response to finasteride in men with symptomatic benign prostatic hyperplasia.},
  author={Leonard S. Marks and Alan W. Partin and Gleen J Gormley and Frederick J. Dorey and E D Shery and Jeffrey B Garris and E N Subong and Elizabeth Stoner and Jean B. Dekernion},
  journal={The Journal of urology},
  year={1997},
  volume={157 6},
  pages={2171-8}
}
PURPOSE We sought to quantify prostate tissue changes induced by finasteride and to identify a predictor of finasteride response in men with symptomatic benign prostatic hyperplasia (BPH) via a randomized, placebo controlled, double-blind clinical trial. MATERIALS AND METHODS Men with symptomatic BPH (52 to 78 years old) were randomly assigned to 6 months of treatment with finasteride (26) or placebo (15). Outcome measures were clinical (urinary symptom score and flow rate), chemical (serum… CONTINUE READING

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