Prostate-specific membrane antigen as a potential novel vascular target for treatment of glioblastoma multiforme.

@article{Wernicke2011ProstatespecificMA,
  title={Prostate-specific membrane antigen as a potential novel vascular target for treatment of glioblastoma multiforme.},
  author={A. Gabriella Wernicke and Mark A. Edgar and Ehud Lavi and He Liu and Pamela Salerno and Neil Harrison Bander and Philip H. Gutin},
  journal={Archives of pathology & laboratory medicine},
  year={2011},
  volume={135 11},
  pages={
          1486-9
        }
}
CONTEXT Prostate-specific membrane antigen (PSMA) is expressed in endothelium of vessels in malignant solid tumors but not in normal vessels. OBJECTIVE To examine whether neovasculature of glioblastoma multiforme (GBM) expresses PSMA. Design.-After institutional review board approval at Memorial Sloan-Kettering Cancer Center, formalin-fixed paraffin-embedded tissue from 32 patients who underwent a maximally safe neurologic resection during 2004 to 2005 for GBM (World Health Organization… CONTINUE READING

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