Prostate specific antigen regression and progression after androgen deprivation for localized and metastatic prostate cancer.

@article{Fowler1995ProstateSA,
  title={Prostate specific antigen regression and progression after androgen deprivation for localized and metastatic prostate cancer.},
  author={Jackson E. Fowler and Prashant Pandey and L E Seaver and T P Feliz and N T Braswell},
  journal={The Journal of urology},
  year={1995},
  volume={153 6},
  pages={1860-5}
}
To identify prostate specific antigen (PSA) functions of prognostic significance in regard to treatment with androgen deprivation for prostate cancer we analyzed the pretreatment PSA, PSA half-life, PSA nadirs, times to PSA elevation and PSA doubling times in 245 patients with localized and 78 with metastatic disease who were treated with this modality. There was a direct correlation between the pretreatment PSA and the time to PSA elevation in patients with localized cancer (p = 0.000003) but… CONTINUE READING
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