Prostate specific antigen only androgen independent prostate cancer: natural history, challenges in management and clinical trial design.

@article{Ryan2007ProstateSA,
  title={Prostate specific antigen only androgen independent prostate cancer: natural history, challenges in management and clinical trial design.},
  author={Castilla Jack Ryan and Tomasz M Beer},
  journal={The Journal of urology},
  year={2007},
  volume={178 3 Pt 2},
  pages={
          S25-9
        }
}
PURPOSE There is no current standard of care for patients with nonmetastatic androgen independent prostate cancer, a condition defined by increasing serum prostate specific antigen despite anorchid testosterone levels and no radiographic evidence of metastases. A consensus panel was convened to review data and propose a strategy for trial design and prioritization. MATERIALS AND METHODS Published literature on the natural history of nonmetastatic androgen independent prostate cancer was… CONTINUE READING
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