Prostate-specific antigen kinetics during follow-up are an unreliable trigger for intervention in a prostate cancer surveillance program.

@article{Ross2010ProstatespecificAK,
  title={Prostate-specific antigen kinetics during follow-up are an unreliable trigger for intervention in a prostate cancer surveillance program.},
  author={Ashley E. Ross and Stacy L. Loeb and Patricia B Landis and Alan W. Partin and Jonathan I. Epstein and Anna Kettermann and Zhaoyong Feng and Herbert Ballentine Carter and Patrick Walsh},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2010},
  volume={28 17},
  pages={2810-6}
}
PURPOSE To assess the predictive ability of prostate-specific antigen (PSA) velocity (PSAV) and doubling time (PSADT) for biopsy progression and adverse pathology at prostatectomy among men with low-risk prostate cancer enrolled on an active-surveillance program. METHODS We evaluated 290 men who met criteria for active surveillance (ie, PSA density < 0.15… CONTINUE READING