Prostate-specific antigen expression in a case of intracystic carcinoma of the breast: characterization of immunoreactive protein and literature surveys.

@article{Mannello1997ProstatespecificAE,
  title={Prostate-specific antigen expression in a case of intracystic carcinoma of the breast: characterization of immunoreactive protein and literature surveys.},
  author={Ferdinando Mannello and Maurizio Sebastiani and Silvia Amati and Giancarlo Gazzanelli},
  journal={Clinical chemistry},
  year={1997},
  volume={43 8 Pt 1},
  pages={1448-54}
}
A case is presented of female breast intracystic carcinoma with prostate-specific antigen (PSA) expressed in high amounts in aspirated cystic fluid (55 micrograms/L). Tumor extract analysis revealed the presence of both estrogen and progesterone receptors (0.38 and 1.87 nmol/L, respectively) and high quantities of PSA too (19.52 micrograms/L). Chromatographic analysis of cystic fluid revealed two peaks of PSA, at the expected positions for free and bound serine protease. A major proportion of… CONTINUE READING

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