Prostate-specific antigen as a serum marker for adenocarcinoma of the prostate.

@article{Stamey1987ProstatespecificAA,
  title={Prostate-specific antigen as a serum marker for adenocarcinoma of the prostate.},
  author={Thomas Alexander Stamey and Norman Yang and Alan R. Hay and John E. McNeal and Fuad S. Freiha and Elise A. Redwine},
  journal={The New England journal of medicine},
  year={1987},
  volume={317 15},
  pages={
          909-16
        }
}
To compare the clinical usefulness of the serum markers prostate-specific antigen (PSA) and prostatic acid phosphatase (PAP), we measured them by radioimmunoassay in 2200 serum samples from 699 patients, 378 of whom had prostatic cancer. PSA was elevated in 122 of 127 patients with newly diagnosed, untreated prostatic cancer, including 7 of 12 patients with unsuspected early disease and all of 115 with more advanced disease. The PSA level increased with advancing clinical stage and was… Expand

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