Prostate-specific antigen and human glandular kallikrein 2 are markedly elevated in urine of patients with polycystic ovary syndrome.

@article{Obiezu2001ProstatespecificAA,
  title={Prostate-specific antigen and human glandular kallikrein 2 are markedly elevated in urine of patients with polycystic ovary syndrome.},
  author={Christina V. Obiezu and Andreas Scorilas and Angeliki Magklara and Melvin H. Thornton and Clare Y Wang and Frank Z. Stanczyk and Eleftherios P Diamandis},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2001},
  volume={86 4},
  pages={1558-61}
}
Prostate-specific antigen (PSA) is a well-established tumor marker of prostatic adenocarcinoma. Human glandular kallikrein 2 (hK2), another serine protease closely related to PSA, is also gaining ground as a promising diagnostic tool in prostate cancer. The expression of these 2 proteases is known to be regulated by androgens and progestins in hormonally responsive tissues, such as the male prostate and the female breast. Previously, we have shown that serum PSA levels in normal women are very… CONTINUE READING