Prostate-specific antigen and 17-hydroxylase polymorphic genotypes in patients with prostate cancer and benign prostatic hyperplasia.

@article{Gunes2007ProstatespecificAA,
  title={Prostate-specific antigen and 17-hydroxylase polymorphic genotypes in patients with prostate cancer and benign prostatic hyperplasia.},
  author={Sezgin Gunes and Hasan Bagci and Saban Sarikaya and Cenk Yucel Bilen and Nurten Kara},
  journal={DNA and cell biology},
  year={2007},
  volume={26 12},
  pages={873-8}
}
We investigated the association of prostate cancer (PCa) and benign prostatic hyperplasia (BPH) with genetic polymorphisms in prostate-specific antigen (PSA) (-158 G/A) and 17-hydroxylase (CYP17) (-34 T/C) genes in a Turkish population. In this study, we investigated the distribution of these polymorphisms in 148 PCa patients, 136 BPH patients, and 102 healthy individuals as controls. The polymorphisms were analyzed using polymerase chain reaction-restriction fragment length polymorphism assay… CONTINUE READING