Prostate-related antigen-derived new peptides having the capacity of inducing prostate cancer-reactive CTLs in HLA-A2+ prostate cancer patients.

@article{Harada2004ProstaterelatedAN,
  title={Prostate-related antigen-derived new peptides having the capacity of inducing prostate cancer-reactive CTLs in HLA-A2+ prostate cancer patients.},
  author={Mamoru Harada and Satoko Matsueda and Akihisa Yao and Rika Ogata and Masanori Noguchi and Kyogo Itoh},
  journal={Oncology reports},
  year={2004},
  volume={12 3},
  pages={
          601-7
        }
}
Prostate-related antigens, including prostate-specific membrane antigen (PSMA) and prostatic acid phosphatase (PAP), can be targets in specific immunotherapy for prostate cancer. In this study, we attempted to newly identify epitope peptides from these 2 antigens, which are immunogenic in human histocompatibility leukocyte antigen (HLA)-A2+ prostate cancer patients. Twenty-nine peptides (PSMA with 15 and PAP with 14) were prepared based on the HLA-A2 binding motif. Based on our previous finding… CONTINUE READING

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