Prostate cancer susceptibility genes: lessons learned and challenges posed.

@article{Simard2003ProstateCS,
  title={Prostate cancer susceptibility genes: lessons learned and challenges posed.},
  author={Jacques Simard and Martine Dumont and Damian Labuda and Daniel Sinnett and Caroline Meloche and Mohamed El-Alfy and Liron Berger and Emma M. Lees and Fernand Labrie and Sean V. Tavtigian},
  journal={Endocrine-related cancer},
  year={2003},
  volume={10 2},
  pages={225-59}
}
In most developed countries, prostate cancer is the most frequently diagnosed malignancy in men. The extent to which the marked racial/ethnic difference in its incidence rate is attributable to screening methods, environmental, hormonal and/or genetic factors remains unknown. A positive family history is among the strongest epidemiological risk factors for prostate cancer. It is now well recognized that the role of candidate genetic markers to this multifactorial malignancy is more difficult to… CONTINUE READING

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