Prostate cancer susceptibility and growth linked to Y chromosome genes.

@article{Patel2018ProstateCS,
  title={Prostate cancer susceptibility and growth linked to Y chromosome genes.},
  author={Riddhi B Patel and Ahmad O. Khalifa and Ilaha Isali and Sanjeev Shukla},
  journal={Frontiers in bioscience},
  year={2018},
  volume={10},
  pages={
          423-436
        }
}
The role of Y chromosome in prostate cancer progression and incidence is not well known. Among the 46 chromosomes, Y chromosome determines the male gender. The Y chromosome is smaller than the X chromosome and contains only 458 genes compared to over 2000 genes found in the X chromosome. The Y chromosome is prone to high mutation rates, created exclusively in sperm cells due to the highly oxidative environment of the testis. Y chromosome harbors epigenetic information, which affects the… CONTINUE READING
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