Prostate cancer stem cells are targets of both innate and adaptive immunity and elicit tumor-specific immune responses

@inproceedings{Jachetti2013ProstateCS,
  title={Prostate cancer stem cells are targets of both innate and adaptive immunity and elicit tumor-specific immune responses},
  author={Elena Jachetti and Stefania Mazzoleni and Matteo Grioni and Alessia Ricupito and Chiara Svetlana Brambillasca and Luca Generoso and Arianna Calcinotto and M. Freschi and Anna Mondino and R Galli and Matteo Bellone},
  booktitle={Oncoimmunology},
  year={2013}
}
According to the cancer stem cell (CSC) theory, therapies that do not target the CSC compartment have limited, if any, chances to eradicate established tumors. While cytotoxic T lymphocytes (CTLs) have the potential to recognize and kill single neoplastic cells within a tissue, whether CSCs can be targeted by the immune system during spontaneous or… CONTINUE READING