Prostate cancer detection by GSTP1 methylation analysis of postbiopsy urine specimens.

@article{Gonzalgo2003ProstateCD,
  title={Prostate cancer detection by GSTP1 methylation analysis of postbiopsy urine specimens.},
  author={Mark L. Gonzalgo and Christian P Pavlovich and Shing M Lee and William Andrew Nelson},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2003},
  volume={9 7},
  pages={2673-7}
}
PURPOSE We assess the feasibility of a urinary test for prostate cancer detection in a high-risk patient cohort based on methylation-specific PCR analysis of the pi class glutathione S-transferase (GSTP1) gene promoter. EXPERIMENTAL DESIGN A total of 45 men underwent transrectal ultrasound-guided biopsy of the prostate for suspected malignancy. Clean-catch voided urine specimens were prospectively collected from each patient immediately after biopsy. Genomic DNA was isolated from urine… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 69 extracted citations

Molecular and clinico-histological data in aggressive prostate cancer patients from Bulgaria.

Journal of B.U.ON. : official journal of the Balkan Union of Oncology • 2015
View 6 Excerpts
Highly Influenced

Precision Molecular Pathology of Prostate Cancer

Molecular Pathology Library • 2018
View 7 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…