Prostate cancer: immunoPET for imaging disease progression in prostate cancer

Abstract

PSCA is highly expressed in most prostate cancers and prostate cancer bone metastases, and its expression has been shown to correlate with Gleason score, tumour invasion, metastasis, androgen independence and prognosis. In an earlier study, Knowles and colleagues showed that immunoPET with a 124I-labelled anti-PSCA A11 minibody (an antibody fragment with… (More)
DOI: 10.1038/nrurol.2014.304

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