Prostanoids in regulation of postprandial jejunal hyperemia and oxygen uptake.

@article{Chou1989ProstanoidsIR,
  title={Prostanoids in regulation of postprandial jejunal hyperemia and oxygen uptake.},
  author={Ching C. Chou and Adamu Alemayehu and Martin J Mangino},
  journal={The American journal of physiology},
  year={1989},
  volume={257 5 Pt 1},
  pages={
          G798-808
        }
}
The role of prostanoids in regulation of jejunal blood flow (JBF) was studied in anesthetized dogs. Intra-arterial infusions of arachidonate produced biphasic changes and dose-dependent decreases in jejunal vascular resistance (JVR) in untreated and aspirin-pretreated dogs, respectively; mefenamate abolished these responses. The jejunum released prostaglandin I2 (PGI2) greater than PGE2 greater than thromboxane A2 (TXA2) (radioimmunoassay) under resting conditions, and food enhanced the release… 
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