Prostanoid-induced relaxation of precontracted cat ciliary muscle is mediated by EP2 and DP receptors.

The pharmacology of prostanoid-induced relaxation of the precontracted cat ciliary smooth muscle was characterized using synthetic prostaglandin (PG) analogues that are selective for specific prostanoid receptors. Relaxation was studied using carbachol to precontract the isolated longitudinal ciliary muscle, followed by application of the PG agonist. Of the… CONTINUE READING