Prostaglandins promote colon cancer cell invasion; signaling by cross-talk between two distinct growth factor receptors.

Abstract

Colorectal cancer is the second most frequent cancer in the Western world, often lethal when invasion and/or metastasis occur. In addition to hepatocyte growth factor (HGF), colon cancer invasion may be driven by prostaglandins, especially the E2 series (PGE2), generated by the cyclooxygenase-2 (Cox-2) enzyme. While concentration of PGE2 as well as… (More)

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Cite this paper

@article{Pai2003ProstaglandinsPC, title={Prostaglandins promote colon cancer cell invasion; signaling by cross-talk between two distinct growth factor receptors.}, author={R. G. Pai and Toshikazu Nakamura and Woo Sung Moon and Andrzej S. Tarnawski}, journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology}, year={2003}, volume={17 12}, pages={1640-7} }