Prostaglandins and the kidney.

@article{Dunn1977ProstaglandinsAT,
  title={Prostaglandins and the kidney.},
  author={Michael J. Dunn and Virginia L. Hood},
  journal={The American journal of physiology},
  year={1977},
  volume={233 3},
  pages={169-84}
}
This review provides a summary and assessment of research involving renal prostaglandins. Arachidonic acid released from phospholipids is converted by prostaglandin cyclo-oxygenase in the kidney to PGF2, PGF2alpha, PGD2, and, possibly, to PGI2 and thromboxane A2. Production of PGE2 and PGF2alpha is predominately but not exclusively in the medulla, whereas degradative enzymes are present in both cortex and medulla. Prostaglandins enter the tubular lumen by facilitated transport and are partially… CONTINUE READING

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