Prostaglandin-related microvascular dilation in pentobarbital- and etomidate-anesthetized rats.

@article{Asher1992ProstaglandinrelatedMD,
  title={Prostaglandin-related microvascular dilation in pentobarbital- and etomidate-anesthetized rats.},
  author={Evan Asher and Nancy L. Alsip and Pei Yan Zhang and Patrick D. Harris},
  journal={Anesthesiology},
  year={1992},
  volume={76 2},
  pages={
          271-8
        }
}
Etomidate is characterized by minimal systemic cardiovascular effects, but its effect on the microvasculature has not been assessed. We compared the microvasculature of etomidate-anesthetized animals to that of animals anesthetized with pentobarbital, since its effects on the microvasculature are known. Male Sprague-Dawley rats were anesthetized with etomidate or pentobarbital. The cremaster muscle was prepared for microscopic viewing, leaving the neural and vascular supply intact. Small… CONTINUE READING
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