Prostaglandin production in response to angiotensin-(1-7) in rabbit isolated vasa deferentia.

@article{Trachte1990ProstaglandinPI,
  title={Prostaglandin production in response to angiotensin-(1-7) in rabbit isolated vasa deferentia.},
  author={George J. Trachte and Karl Meixner and Carlos Maria Ferrario and Mahesh C Khosla},
  journal={Prostaglandins},
  year={1990},
  volume={39 4},
  pages={385-94}
}
Angiotensin-(1-7) is a predominant metabolite of angiotensin I in brain tissue. Its neuromodulatory and prostaglandin (PG) synthesizing capabilities were investigated in the rabbit isolated vas deferens. This metabolite had no significant effect as a neuromodulator, however it increased PGE synthesis in the vasa deferentia with a potency equivalent to that of angiotensin II. The angiotensin-(1-7) has a unique spectrum of activity among the angiotensin peptides to selectively increase PG… CONTINUE READING
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