Prostaglandin in human breast cancer: Evidence suggesting that an elevated prostaglandin production is a marker of high metastatic potential for neoplastic cells.

@article{Rolland1980ProstaglandinIH,
  title={Prostaglandin in human breast cancer: Evidence suggesting that an elevated prostaglandin production is a marker of high metastatic potential for neoplastic cells.},
  author={Pierre Henri Rolland and Pierre M. Martin and Jocelyne D. Jacquemier and A. M. Rolland and Maurice Toga},
  journal={Journal of the National Cancer Institute},
  year={1980},
  volume={64 5},
  pages={
          1061-70
        }
}
Prostaglandin (PG) production by human breast cancers was investigated in 91 lesions selected so that the distribution of histologic type was similar to that of the general population of mammary carcinomas. With regard to the shape characteristics of the tumors, PG production was higher in lesions classified T1 and T2 than in lesions classified T3 and T4 (T-classification is based on extent of tumor as graded by the International Union Against Cancer), higher in tumors exhibiting a high… CONTINUE READING
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