Prostaglandin fever in rats is altered by kainic acid lesions of the ventral septal area.

The ventral septal area (VSA) has been shown to be a region within the rat brain where arginine vasopressin (AVP) acts to reduce fever. To test the hypothesis that destruction of this area would affect the magnitude of the febrile response, body temperature was monitored in male, Wistar rats given intracerebroventricular injections of prostaglandin E1 (200… CONTINUE READING