Prostaglandin endoperoxide-H synthase (PGHS) activity and immunoreactive PGHS-1 and PGHS-2 levels in human amnion throughout gestation, at term, and during labor.

Abstract

Prostaglandins (PGs) are of primary importance in the initiation and maintenance of labor in women. A major intrauterine source of prostaglandins is the amnion, which synthesizes increased amounts of PGE2 at term labor. Because PG endoperoxide-H synthase (PGHS) catalyzes the rate-limiting step of PG synthesis from arachidonic acid, we investigated the… (More)

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Cite this paper

@article{Teixeira1994ProstaglandinES, title={Prostaglandin endoperoxide-H synthase (PGHS) activity and immunoreactive PGHS-1 and PGHS-2 levels in human amnion throughout gestation, at term, and during labor.}, author={Felipe Roberti Teixeira and Tomas Zakar and Jonathan J. Hirst and F. Guo and Drew W Sadowsky and Geoffrey A. Machin and Nestor N Demianczuk and Bastian Resch and Doug Olson}, journal={The Journal of clinical endocrinology and metabolism}, year={1994}, volume={78 6}, pages={1396-402} }