Prostaglandin actions in established insect cell lines

@article{Li2017ProstaglandinAI,
  title={Prostaglandin actions in established insect cell lines},
  author={Yaofa Li and Hongwei Zhang and Joseph A. Ringbauer and Cynthia L. Goodman and Tamra Reall Lincoln and Kaile Zhou and David Stanley},
  journal={In Vitro Cellular \& Developmental Biology - Animal},
  year={2017},
  volume={53},
  pages={421-429}
}
Prostaglandins (PGs) are oxygenated metabolites of arachidonic acid (AA) and two other C20 polyunsaturated fatty acids that serve as biochemical signals mediating physiological functions. We reported that PGs influence protein expression in insect cell lines, which prompted the question: do PGs influence cell proliferation or viability in insect cell lines? Here, we report on the outcomes of experiments designed to address the question in cell lines from three insect orders: Hemiptera (squash… 
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Cell Line Platforms Support Research into Arthropod Immunity
TLDR
Cell line research is a powerful method for understanding how invertebrates mount defenses against pathogenic organisms and testing hypotheses on how these responses occur, providing a tractable, high-throughput, cost-effective, and consistent platform to investigate the mechanisms underpinning insect and tick immune responses.

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