Prostaglandin E2 systemic production in patients with asthma with and without aspirin hypersensitivity.

@article{Mastalerz2008ProstaglandinES,
  title={Prostaglandin E2 systemic production in patients with asthma with and without aspirin hypersensitivity.},
  author={Lucyna Mastalerz and Marek Sanak and Agnieszka Gawlewicz-Mroczka and Anna Gielicz and Adam M {\'C}miel and Andrzej Szczeklik},
  journal={Thorax},
  year={2008},
  volume={63 1},
  pages={27-34}
}
BACKGROUND A special regulatory role for prostaglandin E2 has been postulated in aspirin-induced asthma. A study was undertaken to investigate the effects of aspirin on the systemic production of prostaglandin E2 and cysteinyl leucotrienes in patients with asthma. METHODS The urinary concentrations were determined of two main prostaglandin E2 metabolites… CONTINUE READING