Prostaglandin E2 receptors in abdominal aortic aneurysm and human aortic smooth muscle cells.

Abstract

BACKGROUND Prostaglandin (PG) E(2) (PGE(2)) appears to have a role in stimulating production of interleukin-6 (IL-6) and apoptosis of smooth muscle cells in diseased aortic tissue. These actions are mediated by cellular receptors for PGE(2) EP receptors. OBJECTIVE This study was undertaken to identify EP receptors associated with production of IL-6 by… (More)

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