Prostaglandin E synthase: another enzyme in the cyclooxygenase pathway driving epithelial cancer?

Abstract

COX-2 in Epithelial Cancer COX-1 and -2 metabolize AA and other 20-carbon polyunsaturated fatty acids into PGs, which have a wide array of biological roles that are tissue-specific (1). A variety of exogenous stimuli increase the expression of COX-2 but not COX-1 as a consequence of their distinct transcriptional and translational regulation. Although the… (More)

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Cite this paper

@article{Kurie2001ProstaglandinES, title={Prostaglandin E synthase: another enzyme in the cyclooxygenase pathway driving epithelial cancer?}, author={Jonathan M. Kurie and Roger Dubois}, journal={Clinical cancer research : an official journal of the American Association for Cancer Research}, year={2001}, volume={7 9}, pages={2608-10} }