Prostaglandin D2 controls pulmonary metastasis of malignant melanoma cells

  title={Prostaglandin D2 controls pulmonary metastasis of malignant melanoma cells},
  author={D. R. Strayer'D. A. Stringfellow and Francis A. Fitzpatrick},
Selective metastasis of malignant cells in various neoplastic processes is poorly understood. Metastasis seems to be associated with inherent biochemical and biological properties of tumour cells which guarantee their survival and multiplication. These properties may include surface enzymes1, interaction with various host defence systems and cells2–4, combination with host platelets5, or with the host endothelial cells, and adhesiveness of the metastatic cell. Fidler2,6,7 has developed a series… CONTINUE READING


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