Prostacyclin production in whole blood throughout normal pregnancy.


In a longitudinal study of twelve normal pregnant women the base-line plasma values of 6-keto prostaglandin (PG)F1 alpha, the stable degradation product of prostacyclin, were determined. At the same time the capacity of their blood to produce prostacyclin was assessed using a stimulation test. When collagen is added to citrated whole blood there is a prompt… (More)


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